Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (19) GO Terms (131) Nucleotides (115) Proteins (52) Interactants (328) Wiki
XB-GENEPAGE-481046
???displayGene.symbol???:
 stat3

???displayGene.name???: 
signal transducer and activator of transcription 3 gene 1

???displayGene.synonyms???
aprf , hies , stat3.1 , Xstat3 ( Nomenclature history )

???displayGene.geneFunction???
intracellular signaling

AI Protein Function :
The stat3 protein is a transcription factor activated through phosphorylation in the JAK-STAT signaling pathway. Upon activation, it dimerizes and translocates to the nucleus to regulate the transcript...[+]


InterPro :
STAT TF DNA-bd, p53-like TF DNA-bd, STAT TF alpha, STAT N sf, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
T-cell large granular lymphocyte leukemia [+]

MIM:
HYPER-IgE SYNDROME 1, AUTOSOMAL DOMINANT, WITH RECURRENT INFECTIONS; HIES1 [+]

External Links:
1/2
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info