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Summary Expression Phenotypes Gene Literature (15) GO Terms (36) Nucleotides (141) Proteins (47) Interactants (399) Wiki
XB-GENEPAGE-6033924
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 dot1l

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DOT1-like histone H3K79 methyltransferase

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( Nomenclature history )

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methyltransferase involved in meiosis and transcriptional silencing. DOT1L is the only known, highly conserved enzyme capable of methylating H3K79 in a wide range of species. A role for dot1l in metamorphosis has been demonstrated in Xenopus.

AI Protein Function :
The AI generated protein function for this gene is of poor quality and not shown

InterPro :
SAM-dependent MTases, H3-K79 meTrfase, DOT1 dom

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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