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Summary Expression Phenotypes Gene Literature (45) GO Terms (9) Nucleotides (229) Proteins (55) Interactants (697) Wiki
XB-GENEPAGE-486940
???displayGene.symbol???:
 prickle1

???displayGene.name???: 
prickle planar cell polarity protein 1

???displayGene.synonyms???
prickle , prickle1-a , prickle1-b , prickle A , prickle B , Prickle-b [+] ( Nomenclature history )

???displayGene.geneFunction???
nuclear receptor, may be a negative regulator of the Wnt/beta-catenin signaling pathway [Entrez]

AI Protein Function :
The prickle1 protein is a core planar cell polarity protein functioning in the wnt signaling pathway. It localizes to the cell membrane due to farnesylation and acts as a negative regulator of the cano...[+]


InterPro :
LIM1 prickle, PET domain, LIM3 prickle, Znf LIM, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Unverricht-Lundborg syndrome [+]

MIM:
EPILEPSY, PROGRESSIVE MYOCLONIC, 1B; EPM1B

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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