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Summary Expression Phenotypes Gene Literature (33) GO Terms (96) Nucleotides (268) Proteins (52) Interactants (393) Wiki
XB-GENEPAGE-5918987
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 sqstm1

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sequestosome 1

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p62 ( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein, contains ZZ-type Zn-finger

AI Protein Function :
The sqstm1 gene encodes a selective autophagy receptor protein which binds ubiquitin and LC3, functioning in the sequestration and degradation of ubiquitinated protein aggregates through the autophagy-...[+]


InterPro :
SQSTM UBA, UBA-like sf, PB1 dom, PB1 p62, [+]

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Diseases: 


Disease Ontology:
frontotemporal dementia and/or amyotrophic lateral sclerosis 3 [+]

MIM:
PAGET DISEASE OF BONE 2, EARLY-ONSET; PDB2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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