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Summary Expression Phenotypes Gene Literature (16) GO Terms (30) Nucleotides (167) Proteins (61) Interactants (166) Wiki
XB-GENEPAGE-493607
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 plk4

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polo like kinase 4

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plx4 ( Nomenclature history )

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serine/threonine kinase

AI Protein Function :
The plk4 protein is a serine/threonine kinase that functions as a master regulator of centriole duplication, licensing new centriole assembly through phosphorylation of substrates like STIL. It localiz...[+]


InterPro :
Kinase-like dom sf, POLO box Plk4 2, POLO box Plk4 1, POLO box dom, [+]

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Diseases: 


Disease Ontology:
Seckel syndrome [+]

MIM:
MICROCEPHALY AND CHORIORETINOPATHY, AUTOSOMAL RECESSIVE, 2; MCCRP2

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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