Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (11) GO Terms (64) Nucleotides (221) Proteins (60) Interactants (157) Wiki
XB-GENEPAGE-5909319
???displayGene.symbol???:
 arhgef2

???displayGene.name???: 
Rho/Rac guanine nucleotide exchange factor 2

???displayGene.synonyms???
XLfc ( Nomenclature history )

???displayGene.geneFunction???
guanine nucleotide exchange factor

AI Protein Function :
The arhgef2 protein is a guanine nucleotide exchange factor localized to the cytoplasm and nucleus. It activates Rho GTPases by facilitating the exchange of GDP for GTP. Expression is observed in the b...[+]


InterPro :
PH 16, DH-domain, DBL dom sf, PH domain, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
neurodevelopmental disorder with midbrain and hindbrain malformations

MIM:
NEURODEVELOPMENTAL DISORDER WITH MIDBRAIN AND HINDBRAIN MALFORMATIONS; NEDMHM

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info