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Summary Expression Phenotypes Gene Literature (403) GO Terms (266) Nucleotides (229) Proteins (58) Interactants (1903) Wiki
XB-GENEPAGE-479317
???displayGene.symbol???:
 notch1

???displayGene.name???: 
notch 1 receptor

???displayGene.synonyms???
notch , notch-1 , xnotch , x-notch-1 , xnotch1 , xotch [+] ( Nomenclature history )

???displayGene.geneFunction???
signal transduction, receptor for delta class ligands

AI Protein Function :
The notch1 protein is a transmembrane receptor that localizes to the cell membrane and, upon ligand binding, undergoes proteolytic cleavage to release its intracellular domain which acts as a transcrip...[+]


InterPro :
Notch 1, Notch, EGF-type Asp/Asn hydroxyl site, Notch NODP dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Adams-Oliver syndrome [+]

MIM:
AORTIC VALVE DISEASE 1; AOVD1 [+]

External Links:
GEO Series :
GSE76342.
1/5
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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