Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (6) GO Terms (13) Nucleotides (1309) Proteins (55) Interactants (461) Wiki
XB-GENEPAGE-976314
???displayGene.symbol???:
 idh2

???displayGene.name???: 
isocitrate dehydrogenase 2 (NADP+), mitochondrial

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
NADP-dependent isocitrate dehydrogenase

AI Protein Function :
The idh2 protein is a mitochondrial nadp-dependent isocitrate dehydrogenase enzyme involved in the citrate cycle, catalyzing the oxidative decarboxylation of isocitrate to alpha-ketoglutarate while red...[+]


InterPro :
Isocitrate DH NADP, IsoCit/isopropylmalate DH CS, IsoPropMal-DH-like dom

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
D-2-hydroxyglutaric aciduria [+]

MIM:
D-2-HYDROXYGLUTARIC ACIDURIA 2; D2HGA2

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info