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XB-PHENO-23793

Xtr Wt + LDN-193189, Rankin SA et al. (2012)

Experiment + Assay: Xtr Wt + LDN-193189 + NF42 (immunohistochemistry)
Background: Xtr.inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical 1062368-24-4
NF stage 35 and 36 whole organism
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 42  
Anatomical Phenotypes: abnormal agenesis of trachea, abnormal esophagus morphology
Expression Phenotypes (1):
decreased amount nkx2-1 expression in trachea
Source: fig.S8.d1,d2,d3
Article: XB-ART-45616, PubMed