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XB-PHENO-27372

Xla wt juvenile + skin wound + rCSF1, Garvey Griffith CN et al. (2025)

Experiment + Assay: Xla wt juvenile + skin wound + rCSF1 + juvenile [7dpw] (in situ hybridization)
Background: Xla.outbredXen1
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
amputation/regeneration  
juvenile frog stage skin
protein injection csf1 csf1
 juvenile frog stage skin
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization juvenile frog stage  
Anatomical Phenotypes: increased cell population proliferation in lymphocyte, increased cell population proliferation in migrating macrophage, increased cell population proliferation in neutrophil
Expression Phenotypes (13):
decreased amount ccl4.L expression in wound epidermis
increased amount csf3r.L expression in wound epidermis
increased amount cxcl8a.2.L expression in wound epidermis
increased amount cxcl8a.L expression in wound epidermis
increased amount cxcl8a.S expression in wound epidermis
decreased amount cxcr4.L expression in wound epidermis
increased amount il17re.L expression in wound epidermis
increased amount il17re.S expression in wound epidermis
increased amount il1b.L expression in wound epidermis
increased amount il1b.S expression in wound epidermis
decreased amount il23r.L expression in wound epidermis
increased amount mpo.L expression in wound epidermis
decreased amount tnf.L expression in wound epidermis
Source: Fig. 4. BEH
Article: XB-ART-61650, PubMed