XB-LINE-1055
Line Name: Xla.Tg(hsp70:Xtr.dkk1;cryga:GFP)Jmws
| Summary |
|
| Synonym: |
HGEM-xtDkk1 |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Inbred
|
| Description: |
Heat-shock inducible Dkk1 to down-regulate Wnt/B-catenin signaling with a Gamma crystallin GFP selection marker. |
| Phenotype Description: |
A warm water bath (up to 30 mins) induces dkk1 expression (a wnt-B-catenin antagonist) in spinal cord. Long term expression maintained by 30 min water bath daily. GFP in lens. See image for phenotypic range. |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Jonathon Slack Lab (Jmws) |
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
No
|
| Public: |
Yes
|
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HGEM-DKK1 phenotypes in heat-shocked tadpoles, duration and NF stages of treatments as indicated. Image from MBL embryology course, 2017.
|
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| NXR (US) |
NXR_0021 |
F2 |
|
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