XB-LINE-1548
Line Name: Xtr.tbxt,tbxt.2emJcsm
| Summary |
|
| Synonym: |
t (Xbra) -/+ t2 (Xbra3) -/+, Xtr.tbxt,tbxt.2tmJcsm,Xenopus tropicalis te1.2D/+t2e3.7D/+ |
| Species: |
Xenopus tropicalis |
| Background Strain: |
Xtr.inbred
|
| Paternal Line: |
Xtr.tbxtemJcsm |
| Maternal Line: |
Xtr.tbxtemJcsm |
| Description: |
Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in exon 3 of tbxt.2. Mutations are on the same chromosome, 30kb apart, so are inherited together. |
| Phenotype Description: |
Tailess. Homozygous tailbud stage embryos tbxt (t, Xbra) -/- tbxt.2 (t2,Xbra3) -/- ) do not develop any tail. |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Smith Lab |
| Line Type: |
Mutant |
| Mutated Gene(s): |
tbxt
|
| MTA Required: |
No
|
| Public: |
Yes
|
| Anatomical Phenotypes: |
tbxt |
|
Double Knockout tbtx and tbtx.2 mutant embryos Xtr.tbxt,tbxt.2{tmJcsm} at NF stage 26/27 (left) and NF stage 35/37 (right). Note the phenotype is lack of tailbud formation.
|
|
tbxt/tbxt.2 double TALEN induced mutant X tropicalis embryos [Xtr.tbxt,tbxt.2{tmJcsm}] . showing the tail-less phenotype ( bottom ) compared to wildtype (top) and heterozygous (middle). Scale bar = 0.25mm
|
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| EXRC (Europe) |
EXRC_6021 |
|
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