XB-LINE-1695
Line Name: Xtr.tp53em_del1/em_del2_Vlemx
| Summary |
|
| Synonym: |
tp53168stop |
| Species: |
Xtr.Nigeria |
| Background Strain: |
Xtr.inbred
|
| Description: |
Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del2/+). Both of these deletions are expected to give rise to nonsense-mediated decay since due to the frame-shifting deletion, the premRNA contains a premature stop codon (tp53168STOP). These heterozygous mutants (F1) were subsequently intercrossed to obtain F2 homozygous mutant animals. |
| Phenotype Description: |
|
| Color Morph: |
pigmented |
| Breeding Type: |
UNKNOWN
|
| Lab of Origin: |
Vleminckx |
| Line Type: |
Mutant |
| Mutated Gene(s): |
tp53
|
| MTA Required: |
No
|
| Public: |
Yes
|
| Anatomical Phenotypes: |
tp53 |
| Disease Phenotypes: |
tp53 |
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
|
No availability, contact the Lab of Origin for information about this Xenopus line or strain. Articles using these frogs are listed on the Attribution Tab.
|
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