XB-LINE-801
Line Name: Xla.Tg.(Rno.elas:dnthra-GFP;cryga:GFP)Brown
| Summary |
|
| Synonym: |
Elastase:TRDN-GFP; Elastase::TRDN-GFP3 |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Inbred
|
| Description: |
205 bp rat (Rno) elastase (elas) promoter driving dominant negative (DN) form of the thyroid receptor alpha (thra) (aka TRDN), fused to GFP (fusion indictated by hyphen). pElastase-TRDN-GFP construct was coinjected with Xenopus gamma-crystallin GFP (from Grainger Lab) to produce this double transgenic line. |
| Phenotype Description: |
GFP expression in the pancreas (specifically in the nucleus of the acinar cells of NF54 tadpoles), and in lens. Exocrine pancreases of transgenic tadpoles expressing a dominant negative form of the Thyroid Hormone (TH) receptor controlled by the elastase promoter are resistant to TH. |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Brown Lab |
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
Yes
|
| Public: |
Yes
|
| Catalog Number: |
waiting for EXRC RRID number |
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
|
No availability, contact the Lab of Origin for information about this Xenopus line or strain. Articles using these frogs are listed on the Attribution Tab.
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