XB-LINE-802
Line Name: Xla.Tg(Mmu.col1a2:dnthra-GFP)Brown
| Summary |
|
| Synonym: |
Inducible Collagen:TRDN-GFP |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Inbred
|
| Description: |
DOX inducible. Mouse ( Mmu) collagen (col1a2) enhancer fused to a minimal collagen alpha 2 promoter drives transgene expression in many tissues of developing tadpoles. When induced with Dox, expresses a dominant negative form of the thyroid receptor alpha gene (DNthra) fused to GFP. |
| Phenotype Description: |
GFP expression in cartilage and muscle of limb. GFP expressed widely in young tadpoles, and later at tadpole stages, limb expression is restricted to cartilage and muscle. These animals die at the climax of metamorphosis, before resorbing their tail. |
| Breeding Type: |
UNKNOWN
|
| Lab of Origin: |
Brown Lab |
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
Yes
|
| Public: |
Yes
|
| Catalog Number: |
EXRC Line #26 |
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| EXRC (Europe) |
EXRC_0026 |
|
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