XB-LINE-997
Line Name: Xtr.Tg(WntREs:dEGFP;CMV:dsRed)Vlemx
| Summary |
|
| Synonym: |
pbin7Lef:dGFP F2, pbin7Lef:dGFP-H (F2) |
| Species: |
Xenopus tropicalis |
| Background Strain: |
Xtr.inbred
|
| Description: |
The inserted transgene construct contains a synthetic Wnt-responsive promoter consisting of 7 copies of a TCF/LEF1 binding DNA element, a minimal TATA box and a reporter gene encoding destabilized EGFP and a polyA sequence. The transgene is flanked on both sides by two copies of the chicken HS4-core sequence. See Tran et al., 2010 and 2013 for a full description. Likely due to a (unknown) transgene integration event, the animals can produce pseudo-albino (no red eyes) off-spring. |
| Phenotype Description: |
GFP expression reveals dynamic patterns of Wnt/beta-catenin signaling activity
First clear signals present at neurula stage (NF stage 19) in the neural folds.
|
| Color Morph: |
albino |
| Breeding Type: |
UNKNOWN
|
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
No
|
| Public: |
Yes
|
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
|
No availability, contact the Lab of Origin for information about this Xenopus line or strain. Articles using these frogs are listed on the Attribution Tab.
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